Activation of neuronal CB1 receptors results in inhibition of adenylyl cyclase and decreased neurotransmitter release by blockade of voltage-operated calcium channels.[forty six,sixty five,125] The activation of those signaling pathways by CB1 receptors as well as the high levels of these receptors on presynaptic terminals implies that endocannabinoid stimulation of CB1 https://rafaelrdqoa.bloguetechno.com/detailed-notes-on-thc-68064589