Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors within the central anxious procedure, conolidine modulates alternate molecular targets. A Science Advances review uncovered that conolidine interacts With all the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabi... https://socialbuzztoday.com/story6071506/a-review-of-alternative-natural-pain-relief-to-replace-traditional-painkillers