Exploration into conolidine has resulted in discovery of an opioid receptor in the body identified as ACKR3/CXCR7. ACKR3 seems to be the most desired target for conolidine, which also disregards another four classical opioid receptors(3). Conolidine has become located in the tabernaemontana divaricata plant, that is inside the Apocynaceae https://bookmarkspiral.com/story20841689/alternative-natural-pain-relief-to-replace-traditional-painkillers-options